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The optimal timing for endoscopic retrograde cholangiopancreatography (ERCP) for acute cholangitis (AC) has not been unequivocally established. To perform a meta-analysis of the outcomes associated with particular timings of ERCP for AC. A systematic literature search was conducted for studies of ERCP for AC, and then a meta-analysis of the in-hospital mortality (IHM), 30-day mortality, and length of hospital stay (LHS) was performed. Seven non-randomized studies of 88,562 patients were considered appropriate for inclusion. Compared with