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Esophageal wall tension is greater in the Trendelenburg position and with viscous bolus as compared with the supine position and saline bolus. The esophageal wall distensibility is larger in the distal as compared with proximal esophagus, which is true for both the saline and viscous bolus. We report, for the first time, bolus flow rate and biomechanical properties of the esophageal wall during swallow-induced primary peristalsis. Future studies may investigate biomechanical basis of esophageal motility disorders using the methodology