https://www.selleckchem.com/pr....oducts/serotonin-hcl
Homeostatic CD101- eosinophils ameliorated, while allergic CD101+ eosinophils exacerbated, the neutrophilic inflammation induced by LPS. Likewise, CD101 expression in eosinophils from ARDS patients did not differ from the healthy subjects. Mechanistically, CD101- eosinophils exhibited higher levels of Alox15 and Protectin D1. Administration of Protectin D1 isomer attenuated the neutrophilic inflammation. Conclusions Collectively, our findings identify an uncovered function of native CD101- eosinophils in suppressing neutrophilic l