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1 ± 1.6 in SLE, 0.001) and more severe disease as defined by the Katz index (3 ± 1.8 in SLE-APS, 2.7 ± 1.7 in SLE-aPL and 2.6 ± 1.6 in SLE, 0.001). SLE-APS patients showed higher mortality rates ( 0.001). SLE-APS patients exhibited more severe clinical profiles with higher frequencies of major organ involvement, greater damage accrual and higher mortality than SLE-aPL and SLE patients. SLE-APS patients exhibited more severe clinical profiles with higher frequencies of major organ involvement, greater damage accrual a