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Positive HIV status was not associated with increased risk of intraoperative complications. Post-operative CDVA was better in the HIV negative group compared to the HIV+ group but not significantly different (about 20/24 vs. 20/28, p = .0829). Eyes from HIV+ patients were at increased risk of developing PAU after surgery (adjusted OR = 6.04, 95% CI 2.42-15.1, p = .0001), as well as CME (adjusted OR = 3.25, 95% CI 1.02-10.4, p = .047.Conclusions Eyes from HIV+ patients were at greater risk of developing PAU and clinically significant CM