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Particularly, a rise in FGF9 and β-catenin protein appearance and a decrease in APC protein phrase had been observed in the founded LoVo cisplatin resistant cell line (LoVo/cisplatin). Silencing of FGF9 reversed cisplatin resistance of LoVo/cisplatin cells. In summary, the present findings suggested that FGF9 triggered the Wnt signaling pathway and had been a mediator of cisplatin opposition in colorectal cancer. Copyright © Zhang et al.Heart condition remains the leading reaso