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Both entities revealed exceptional outcome with general survival of 100per cent whenever managed in accordance with NHL-BFM techniques and could provide prospects for future therapy de-escalation in clinical tests. © 2020 The Authors. British Journal of Haematology published by British Society for Haematology and John Wiley Sons Ltd.OBJECTIVE Early onset epileptic encephalopathy with suppression-burst is one of the most severe epilepsy phenoty