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Challenges of ADHD in Women and Girls Girls and women often face a wide range of challenges when untreated ADHD symptoms interfere with their daily lives. They may feel inadequate at work, have difficulty in social relationships, or suffer from depression and anxiety. They also tend to be better in establishing coping mechanisms that mask their ADHD symptoms, making it difficult to be diagnosed and treated. Symptoms The gender gap in ADHD is narrowing as people age. It i