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One of the most misdiagnosed appendicular pathologies is lymphoid hyperplasia (LH) that can be managed con-servatively when identified early and is self-limiting. The aim of this retrospective study was to compare acute appendicitis (AA) with LH in terms of hematological parameters to determine whether there is a hematological predictor to distinguish the two diseases. Complete blood cell counts of patients with AA were compared with those having LH. One-hundred-ninety-five patients (118 male/77 female) underwent appendectomy. Histopath