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Medications For ADHD The most commonly prescribed treatment for ADHD is stimulants. They can be used quickly to improve attention and reduce impulsivity and hyperactivity. They can cause negative side effects, such as headaches, stomach upsets, and changes in blood-pressure and heart rate. Amphétamines and methylphenidates are the two main classes of stimulants. They are available in liquid or chewable form, and as short-acting, intermediate-acting, or long-acting drugs. Stimulants Stimulants