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Polycystic ovary syndrome (PCOS) is a reproductive system disease with high incidence in women of childbearing age. However, the cause and risk factor are not clear. Our study aims to explore whether IL-17A gene polymorphism rs2275913 is associated with the PCOS in women from Yunnan province, China. From January 2018 to December 2020, we collected 287 specimens from PCOS patients and 279 specimens from healthy women. The rs2275913 in the IL-17A promoter region were detected by PCR-Sanger sequencing. Detailed clinical symptoms were record