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In this Minireview, we discuss present discoveries made applying state-of-the-art AFM processes to microbial specimens in order to comprehend the power and dynamics of adhesive interactions. These scientific studies lose new-light in the molecular components of adhesion, and show an intimate relationship between force and purpose in microbial adhesins. Copyright © 2020 American Society for Microbiology.Potassium and glutamate are the significant ca