https://www.selleckchem.com/pr....oducts/proxalutamide
pathology; however, direct comparisons of popular models are not available. In this study, we compared adenine-induced nephropathy and 5/6 nephrectomy models. Both models produced equivalent levels of muscle atrophy and mitochondrial impairment, but the adenine model exhibited lower mortality rates, higher consistency in uremic toxin levels, and dysregulated phosphate homeostasis compared with the 5/6 nephrectomy model.We used male BTBR mice carrying the Lepob mutation, which are subject to severe and progressive obesity an
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