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We conclude that MRN promotes stringent homologous recombination at subtelomeric loci and restrains antigenic variation. Limitations in the sensitivity and accessibility of diagnostic tools for childhood tuberculosis contribute to the substantial gap between estimated cases and cases notified to national tuberculosis programs. Thus, tools to make accurate and rapid clinical diagnoses are necessary to initiate antituberculosis treatment in more children. We analyzed data from a prospective cohort of children 13 years old being routin
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