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rfusion and relative change rates of blood flow perfusion, which facilitated the differentiation of the four acupuncture manipulation methods. Based on this, further analysis could be conducted to study spatial distribution characteristics such as the influence area and flare area. The frequency domain analysis of acupuncture manipulation curves is important in the study of the dose-effect relationship and specificity of acupuncture manipulation.OBJECTIVE To investigate effect of Qushi Xiezhuo formula (QSXZF) on axial spondyloarthritis (AxS
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