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10 ms or less between samples. This rate fits the data acquisition speed of contemporary high-performing size spectrometers whereas the pulse repetition rate associated with lasers (1 kHz) provides a sufficient number of desorption/ionization events for effective ion signal recognition from each test during the above speed of the sample phases. Other features of laser-based ionization methods are the generally speaking greater tolerance to sample ingredients and contamination compared with ESI MS, and the contac
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