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ecture and bone strength features in long bones. © 2021 American Society for Bone and Mineral Research (ASBMR). Tenofovir disoproxil fumarate (TDF) is a first-line treatment for chronic hepatitis B virus (HBV) infection for its high potency and a low rate of drug resistance. This study investigated the efficacy and safety of TDF in Chinese patients with chronic hepatitis B (CH infection after treatment failure with multiple nucleos(t)ide analogues (NAs). Patients included were aged 18-65years, with treatment failure with multiple NAs
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