https://www.selleckchem.com/pr....oducts/cloperastine-
1 vs. 102.6 ng/mL; p=0.2, AUC from time 0 to infinity (99.7 vs. 114.3 ng·h/mL; p=0.18), AUC from 0 to 24 h post-dose (AUC0-24; 49.4 vs. 51.6 ng·h/mL; p=0.56), time to reach maximum blood concentration (median, 6.0 vs. 6.0 h; p=0.91), total clearance (arithmetic mean = 21.5 vs. 19.5 L/h; p=0.5, or terminal half-life (arithmetic mean = 26.8 vs. 28.1 h; p=0.26). After a high-calorie meal in the morning, the AUC0-24 reduced by 54% (ratio of geometric means = 45.6%; p less then 0.0001) and peak blood concentration reduced
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