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© Copyright 2020 Physicians Postgraduate Press, Inc. to be able to recognize inadequate reaction to antidepressant treatment and differentiate it from treatment-resistant despair is key in order for physicians to provide appropriate therapies. Although definitions differ, nonresponse is usually thought as less than 25% enhancement on a standardized rating scale, and partial response, as more than 25% but lower than 50% improvement. Residual symptoms characteristic of inadequ
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