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Link between 598 researches screened, 101 were eligible 16 were prospective (15.8%). The qualified scientific studies included a total of 5,545 NEN customers, with a median of 39 clients per study (range 5-214). Pooled rate of partial response had been 36.6% (38.9% accomplished stable infection) and 55.2% of customers had a symptomatic a reaction to treatment when pooled information were analysed. The median PFS and OS had been 18.4 months (95% CI 15.5-21.2) and 40.7 months
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