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There have been no variations in general (OS) and disease-free survival (DFS) of HIF-1α expression in main CRC. Nonetheless, HIF-1α phrase in liver metastasis correlated to poor prognosis both in OS and DFS. Furthermore, patients with HIF-1α positive expression in liver metastasis had bad prognosis. HIF-1α expression in liver metastasis determines poor prognosis of CRLM customers. HSCs might play a key part in aggressive phenotypes of tumor cells.HIF-1α phrase in liver metastasis determines bad prognosis o
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