https://www.selleckchem.com/pr....oducts/ro-31-8220-me
To investigate mechanisms of primordial follicle (PMF) loss invivo in human ovaries shortly after alkylating agent (AA) chemotherapy. Cohort study. Tertiary university medical center. Ninety-six women aged 15-39 years who underwent ovarian tissue cryopreservation for fertility preservation. Fresh ovarian tissue samples were harvested from women treated with AA (n = 24) or non-AA (n = 24) chemotherapy 6 months after treatment and age-matched untreated women (n = 48). Differential follicle counts, time from chemotherapy ex
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