https://sodiumchannel-signal.c....om/inflammatory-myof
DDX5 acts to potentiate Tat task and certainly will bind both Tat and HEXIM1 recommending it could facilitate the dissociation of HEXIM1/2 from the 7SK-snRNP complex, boosting Tat/P-TEFb availability. We reveal knockdown of DDX5 in a T cell range considerably lowers HIV-1 infectivity and viral protein manufacturing. This activity is unique to DDX5 and cannot be replaced by its close paralog DDX17. Overexpression of DDX5 stimulates the Tat/LTR promoter but suppr
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